The safety standards travelers might expect of adventure tour operators are not always met in Zambia. Sufficient life jackets and adequate safety equipment may not be provided.
By far the most dangerous part of Zambia are the borders with Angola, Mozambique and the Democratic Republic of Congo. You should seriously reconsider your need to travel to these areas as the risk of landmines is very high.
First up, be warned: the standard of medical facilities is poor, especially in rural areas. Medical supplies are limited and some prescription medicines may not be available.
Drugs, porn and homosexual sex are all illegal in Zambia and severely punished. The possession or use of narcotics, including soft drugs such as marijuana, is strictly prohibited.